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This article lists the Line-of-Business (LOB) systems supported by BizTalk Server. Yes means it's supported. No means it's not supported.

Supported means that the LOB system has been tested by the BizTalk product group. If it's not supported, that LOB system has not been tested. The LOB system may still work, even if it's technically not supported.

SAP Server
 BizTalk 2013   BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 SAP R/3 4.6c Non-Unicode  Yes  Yes  Yes  Yes
 SAP R/3 4.7 Non-Unicode  Yes  Yes  Yes  Yes
 SAP R/3 4.7 Unicode  Yes  Yes  Yes  Yes
 SAP ECC 5.0 Non-Unicode  Yes  Yes  Yes  Yes
 SAP ECC 5.0 Unicode  Yes  Yes  Yes  Yes
 SAP ECC 6.0 Unicode  Yes  Yes  Yes  Yes
 SAP ECC 6.0 Unicode with EHP 4.0  Yes  Yes    
 SAP ERP 6.0 with EHP 6.0 and all EHP previous versions  Yes  Yes    
 SAP 7.2  Yes  No    
 SAP 7.3  No      

SAP Client
 BizTalk 2013   BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 SAP RFC SDK 6.4 UNICODE  Yes  Yes  Yes  Yes
 SAP RFC SDK 7.0 UNICODE  Yes  Yes  Yes  Yes
 SAP RFC SDK 7.1 UNICODE  Yes  Yes  Yes  Yes
 SAP RFC SDK 7.11 UNICODE  Yes  Yes    
 SAP RFC SDK 7.20 UNICODE  Yes  Yes    

Oracle Database
 BizTalk 2013   BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 Oracle database 9.2  No  Yes  Yes  Yes
 Oracle database 10.1  No  Yes  Yes  Yes
 Oracle database 10.2  Yes  Yes  Yes  Yes
 Oracle database 11.1  Yes  Yes  Yes  No
 Oracle database 11.2  Yes  Yes  No  No

Oracle Client
   BizTalk 2013  BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 Oracle Client  No  No  No  Yes
 Oracle Client with Patch Set  No  Yes  Yes  No
 Oracle Client  Yes  Yes  No  No
 Oracle Client  Yes  Yes  No  No

Oracle E-Business Suite
   BizTalk 2013  BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 Oracle EBS 11.5.9  No  Yes  Yes  
 Oracle EBS 11.5.10  Yes  Yes  Yes  
 Oracle EBS 12.0  Yes  Yes  Yes  
 Oracle EBS 12.1  Yes  No  No  

Siebel Server
   BizTalk 2013  BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 Siebel 7.5 ( + Quick Fix[16285]QF0H05)  No  Yes  Yes  Yes
 Siebel 7.7 (  No  Yes  Yes  Yes
 Siebel 7.8 (  Yes  Yes  Yes  Yes
 Siebel 8.0 (  Yes  Yes  Yes  Yes
 Siebel 8.1  Yes  No  No  No

Siebel Client
   BizTalk 2013  BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 Siebel Web Client 7.5  No  Yes  Yes  Yes
 Siebel Web Client 7.7  No  Yes  Yes  Yes
 Siebel Web Client 7.8  Yes  Yes  Yes  Yes
 Siebel Web Client 8.0  Yes  Yes  Yes  Yes
 Siebel Web Client 8.1  Yes  No  No  No

SQL Server
   BizTalk 2013  BizTalk 2010  BizTalk 2009  BizTalk 2006 R2
 SQL Server 2000  No  Yes  Yes  
 SQL Server 2005  Yes  Yes  Yes  
 SQL Server 2008  Yes  Yes  Yes  
 SQL Server 2008 R2  Yes  Yes  No  
 SQL Server 2012  Yes  No  No  

Note: This refers to the SQL Server versions used by the SQL adapters in the BizTalk Adapter Pack. For the SQL Server versions supported as the back-end system to BizTalk Server, refer to the BizTalk Server installation guide specific to your BizTalk Server version.

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