Monitoring BizTalk can be done using SCOM or HP OpenView by administrators and issues can be diagnosed and resolved using BizTalk administration console with or without combination of other tools (BizTalk Server 2010 - Tools). To use SCOM solely for BizTalk monitoring might be too costly for mid-sized organization or even an enterprise. The product requires highly skilled people to implement and operate SCOM, and it has a steep learning curve. Besides the skillset it also requires an investments in fair amount of hard- and software. Since SCOM can monitor any Microsoft product, Azure and third-party products it would be waste of resources to just use SCOM for monitoring BizTalk. SCOM be a perfect combination with some tools listed in this article and/or HP OpenView.
BizTalk Processing Monitor (or BPM) tool enables you to monitor message flow through your BizTalk systems. Most monitoring software mentioned in this article monitor for example the availability of endpoints. Important to know if your endpoints are up-and-running, yet this does not guarantee that messages actually are flowing through your system. BPM provides that insight and in case of any interruptions, the user will got notified. Tool is currently in its public beta.